R&D

Developing innovative therapeutics based on next-generation mRNA·LNP platform technology.

Platform Technology

SML Biopharm possesses an mRNA platform with optimized UTR and poly(A) tail for enhanced stability and expression efficiency. While advancing next-generation mRNA platforms and new drug pipelines, we are independently developing lipid nanoparticles (LNP) for efficient delivery, leading effective R&D and rapid research progress.

mRNA Platform Technology

Immunotherapy

Immunotherapy

Induces immune response and treatment by expressing specific antigens through mRNA. Various new drug development including prophylactic vaccines and cancer vaccines is possible.

Immune response induction and treatment through specific antigen expression via mRNA
Various new drug development including prophylactic vaccines and cancer vaccines

In vivo Protein Therapeutics

Expresses specific peptides or proteins (antibodies, enzymes, etc.) for disease treatment. Target protein production is much simpler and more efficient, and can be applied to various diseases including infectious diseases, cancer, genetic diseases, and rare diseases.

Expression of specific peptides/proteins for disease treatment (antibodies, enzymes, etc.)
Much simpler and more efficient target protein production
Applicable to various diseases including infectious diseases, cancer, genetic diseases, and rare diseases
In vivo Protein Therapeutics

Pipeline

We are developing innovative therapeutics for various diseases based on mRNA platform technology.

SML Biopharm Pipeline

Development Process

We develop innovative therapeutics through systematic R&D processes.

Discovery

Target discovery and<br>candidate exploration

Preclinical

Preclinical testing and<br>efficacy/safety validation

Clinical Trial

Clinical trials<br>(Phase 1-3)

Regulatory

Regulatory submission<br>and approval

Commercialization

Commercialization and<br>market launch

Patents & Publications

We secure innovative technologies through continuous R&D.

Patent

Core LNP Composition Technology for mRNA Vaccines

Technology transfer from MFDS

Conference

Development of Therapeutic Antibodies In Vivo

4th mRNA-Based Therapeutics Summit Europe, Germany

Technology

SFTS Virus Neutralizing Antibody Sequence

License acquired from AI BIO (Developed by Prof. Jun-Ho Jung, SNU)

Publication

Development of SFTS Therapeutics Using mRNA-LNP Platform

Journal of Virology, 2024

Patent

mRNA Construct Comprising Optimized UTR Sequences

Korea Patent Application

Research Collaboration

SML Biopharm accelerates innovative therapeutic development<br>through collaboration with domestic and international research institutions and companies.